Abstract: REBaCuO (RE=Y, Gd and other rare earth elements) high-temperature superconducting coated conductors, also known as second-generation high-temperature superconducting (2G-HTS) tapes, have been produced based on the development of film epitaxy and biaxial texture growth on flexible metal substrates. This technology has solved the problems of weak-linking at grain boundaries and the difficulties of mechanical processing for such HTS ceramics, which are excellent practical high- temperature superconducting materials with superior electromagnetic performance at liquid nitrogen temperatures. This article first summarizes various methods of fabricating 2G-HTS tapes and their current status at home and abroad, then introduces the key processing technologies in the preparation of long tapes by using a low- cost chemical solution method. Finally, the latest research on magneto-transport anisotropy, flux pinning and their artificial modulation are reviewed with regard to the application of REBaCuO coated conductors under strong magnetic fields and high current.