Abstract: Quantum simulation, as a novel“bottom-up”research paradigm, addresses the challenges of high complexity and difficult controllability in current materials science, thereby facilitating innovative research on new materials. By utilizing systems such as ultracold atoms, quantum simulation—integrated with techniques like optical lattices, synthetic gauge fields, and Raman coupling—enables the emulation of important quantum states including hightemperature superconductivity, topological insulators, and topological superconductors. This approach provides effective support for the development of a wide range of functional materials, such as superconducting, topological, and two-dimensional materials.