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声动力学疗法治疗肿瘤的研究现状及前景

THE STATUS AND PROSPECTS OF TUMOR TREATMENT WITH SONODYNAMICS

  • 摘要: 由于光在人体组织中穿透能力差,光动力学疗法治疗肿瘤主要集中在人体表面浅层部位.为了克服光动力学疗法治疗肿瘤的局限性,利用超声激活血卟啉进行抗肿瘤效应(即声动力学疗法)已成为近几年国内外研究者关注的热点之一.文章就声动力学疗法治疗肿瘤的研究现状、研究方法、实验结果以及作用机理进行了扼要综述,分析了阻碍声动力学疗法临床应用存在的问题,并对问题的解决和未来发展趋势提出了自己的见解.

     

    Abstract: Photodynamic treating tumors focuses on people′s superficial tissue region due to the lack of laser light penetration into tissue. In order to overcome photodynamic treatment limitation, the anti-tumor effect of hematopophyrin derivatives activated by ultrasound (namely: sonodynamic treatment) has been a hot research area which has attracted much attention both home and abroad in recent years. This paper introduces the progress of study ,the research results, the experiment method and the theory of tumor treatment with sonodynamic method. Existing problem of the clinical application and the future development prospect have been discussed.

     

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